According to the Civil Protection Directorate, 30 percent of the coronavirus tests conducted over the past 24 hours came back positive, resulting in 2,599 new infections.
Fifty virus-related deaths were also recorded over the same period - the most so-far this year. There are currently 1,768 Covid-19 patients being treated in hospital; 175 of whom are on ventilators.
Despite the large number of new cases, the director of the Croatian Institute of Public Health, Krunoslav Capak, said there are 9 percent fewer infections this week compared to last.
"The average incidence rate for Croatia 593.3; based on 14 infections per 100,000 inhabitants. The lowest incidence rate is in Istria County 104.4; while the highest is in Primorje-Gorski Kotar County with 1,438," said Capak
The head of the Civil Protection Directorate, Interior Minister Davor Božinović, said the worsening epidemiological situation could lead to stricter measures across the country in order to preserve the upcoming summer tourism season.
Health Minister Vili Beroš once again pleaded with the public to have faith in vaccinations. In a specific reference to the AstraZeneca vaccine - which the European Medicines Agency confirmed was linked to a rare blood clotting issue - the minister said all medicines had potential side effects, but that they were much safer than the virus itself.
Prime Minister Andrej Plenković also called on everyone to get vaccinated.
"The message to my fellow citizens is to get vaccinated. If you are able, if you are called, and if you are part of the third phase of vaccinations, get vaccinated. Vaccinations are good," said the prime minister.